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Francesco Bossi UNIPI Presents TOLIFE

TOLIFE Work Showcased at MetroXRAINE 2025

By Articles, News, Public Events No Comments

30 October 2025

Francesco Bossi, researcher at the University of Pisa and contributor to the TOLIFE Project, recently presented his latest work at MetroXRAINE 2025 in Ancona, Italy. The presentation was part of the thematic session Emerging Technologies for Health Monitoring and Personalized Medicine.

His talk, titled “FEV1 Trajectory Classification in COPD Patients”, focused on how wearable sensor data and machine learning can support continuous monitoring of lung function decline in individuals with Chronic Obstructive Pulmonary Disease (COPD). As COPD remains one of the leading causes of morbidity worldwide, early detection of disease progression is crucial to improve clinical outcomes and patient quality of life.

The conference offered an important opportunity to engage with researchers working on advanced solutions for proactive, continuous, and patient-centred healthcare. The work showcased by Bossi highlights TOLIFE’s commitment to leveraging innovative data-driven approaches to support effective disease management.

TOLIFE 3rd GA in Bologna

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9 October 2025

The TOLIFE consortium gathered in Bologna for the third in-person General Assembly since the project’s beginning. The meeting, hosted by Tinexta Innovation Hub | beWarrant, brought together all partners to review progress, discuss ongoing activities, and plan the next steps for the coming months.

The session was opened by Alessandro Tognetti, project coordinator, who provided an overview of the work accomplished so far and outlined the roadmap ahead. He also welcomed the representatives of Thorax Foundation, the newest member of the consortium, who introduced themselves and their contribution to the project.

Throughout the meeting, partners presented updates from their respective work packages, covering a wide range of topics from the clinical aspects to the development of smart sensors and the user interface. The discussions highlighted the collaborative spirit of the consortium and the shared commitment to advancing innovative digital solutions for respiratory health.

Both patients and members of the Advisory Board expressed their satisfaction with the project’s progress, emphasizing their appreciation for being actively involved in the work and for the continuous and meaningful engagement ensured by the consortium.

The General Assembly also served as an important step in preparation for the upcoming Review Meeting, which will take place in the following weeks.

Second Press Release Published

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29 November 2024

The TOLIFE project, now two years in, has published its second press release, highlighting the successful development of non-invasive devices and the commencement of Clinical Study A. This pivotal phase marks a significant step toward revolutionizing COPD care through AI-driven, personalized solutions.

Read the full press release to discover how these innovations are shaping the future of chronic disease management.

TOLIFE at BRIGHT-NIGHT: Showcasing Innovation in Research

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01 October 2024

On September 27, 2024, TOLIFE proudly participated in the European Researchers’ Night, known as BRIGHT-NIGHT, a prestigious event organized across Europe. This initiative, created by the European Commission, aims to promote scientific culture and showcase the societal impact of research.

BRIGHT-NIGHT stands for Brilliant Researchers Impact on Growth Health and Trust in research, highlighting the crucial role that talented researchers play in advancing science and fostering public trust. It serves as an opportunity for people of all ages to connect with the world of science and meet the dedicated individuals who have made research their daily mission.

In Padua, the CNR (National Research Council) participated, presenting cutting-edge developments in science and innovation, including the devices from the TOLIFE project. These devices were showcased to the public, offering an up-close look at the groundbreaking technology designed to improve health and well-being.

TOLIFE’s involvement in this significant event underlines the project’s commitment to impactful research and its dedication to enhancing quality of life through innovative scientific solutions. BRIGHT-NIGHT was not only an inspiring celebration of research but also a step forward in bringing science closer to communities and sparking curiosity about the world of discovery.

TOLIFE Group picture in Madrid

TOLIFE Project General Assembly in Madrid

By News, Technical meeting No Comments

28 September 2024

The TOLIFE project convened its General Assembly at the Universidad Politécnica de Madrid on September 25-26, bringing together researchers, project partners, and patient representatives to assess the progress and define future strategies.

The first day began with presentations on key Work Packages, focusing on Project Management, Communication, and the development of critical components such as Analytics Tools, Smart Sensors, and the Collection Platform. In the afternoon, the discussions shifted to refining these technical elements, particularly exploring ways to enhance software interfaces and expand the project’s analytical capabilities. A highlight of the day was the involvement of the Patient Advisory Group, whose feedback reaffirmed the importance of maintaining a patient-centered approach throughout the project.

The second day featured a deep dive into the legal and ethical aspects of AI technology within the context of the TOLIFE project. A dedicated workshop on the EU Artificial Intelligence Act sparked engaging conversations on compliance and the ethical use of AI, helping the team align on best practices and regulatory considerations.

The two-day assembly fostered meaningful dialogue and set clear priorities for the next phases, ensuring that TOLIFE continues to advance in its mission to improve patient outcomes through cutting-edge technology and research.

TOLIFE Project Kicks Off Clinical Study A for COPD

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9 July 2024

The TOLIFE project, aimed at revolutionizing the management of Chronic Obstructive Pulmonary Disease (COPD), has officially commenced its Clinical Study A. This milestone marks a significant step forward in the project’s mission to enhance the quality of life for COPD patients through personalized treatment and advanced technological solutions.

The Role of AI in COPD Management

TOLIFE leverages artificial intelligence (AI) to process daily life patient data captured by unobtrusive sensors. This AI-driven approach is designed to optimize personalized treatment, assess health outcomes, and ultimately improve the quality of life for COPD patients. By predicting and mitigating exacerbations, the TOLIFE platform aims to reduce mortality, enhance health-related quality of life, and lower healthcare costs.

Clinical Study A: A Key Component of TOLIFE

Clinical Study A is a crucial element of the TOLIFE project. The recruitment started in June 2024 and each participant will be monitored for 12 months. This study will focus on registering exacerbations and conducting periodic clinical examinations to provide essential clinical references for the AI tools being developed. The data collected from this study will be instrumental in:

  1. Developing a model to detect severe COPD exacerbations at an early stage.
  2. Creating a model to assess the impact of COPD and its comorbidities on patients’ health status and quality of life.

Progress and Next Steps

The Clinical Study A has successfully begun, with all necessary smart sensor kits delivered to Germany and Spain. Patients have started participating in the trial, and the platform is already collecting initial data for analysis. This early data collection is a promising start, indicating that the TOLIFE platform is on track to deliver valuable insights and improvements in COPD management.

By integrating advanced AI technologies with patient care, TOLIFE aspires to set a new standard in managing chronic diseases like COPD. The project’s commitment to enhancing patient outcomes through innovative solutions continues to drive its efforts forward.

Stay tuned for more updates on the progress and findings of Clinical Study A and other initiatives under the TOLIFE project.

Professor Tognetti presents TOLIFE Project at Robotics Festival in Pisa

TOLIFE Project presented at Robotics Festival in Pisa

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26 May 2024

Professor Tognetti, the coordinator of the TOLIFE Project, presented an engaging talk at the renowned Pisa Robotics Festival.

The presentation, titled “Intelligent Sensors and Artificial Intelligence for Managing Complex Chronic Diseases: The TOLIFE Project,” showcased the innovative work being done to transform healthcare management through advanced technology.

The TOLIFE Project aims to clinically validate an artificial intelligence (AI) solution to enable optimized and personalized treatment for patients with complex chronic diseases, with a particular focus on chronic obstructive pulmonary disease (COPD). By analyzing daily patient data captured from non-invasive smart devices (such as smartwatches, smartphones, smart mattress covers, smart shoes, and environmental units), TOLIFE predicts exacerbations, assesses patient health outcomes, and characterizes patient health status.

During the talk, Professor Tognetti provided an in-depth overview of the non-invasive smart devices selected for the TOLIFE clinical studies. The discussion emphasized the data collection framework, the rationale behind selecting each specific sensor, the raw data associated, and the health parameters detected.

The event garnered significant attention, drawing experts and enthusiasts from the fields of robotics and healthcare technology. Positive feedback highlighted the audience’s interest in the potential applications of TOLIFE’s cutting-edge solutions.

Stay updated with more news on the TOLIFE project as we continue to innovate in healthcare technology.

For more information about the festival and other talks, visit the Robotics Festival website here.

The first TOLIFE Comic is out now!

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3 April 2024

In a collaborative effort spearheaded by ISGlobal, a compelling comic has been developed as part of the TOLIFE project, aimed at advocating good lung health and raising awareness about the hazards of tobacco consumption. This initiative involved a diverse array of stakeholders including patients, caregivers, and student groups.

The comic, available in Spanish, Catalan, and English, portrays a man smoking on a park bench amidst lush greenery. As he reminisces about his youthful days playing football, he decides to join a group of kids on the field. Despite showcasing his football abilities, his smoking habit becomes a hindrance, forcing him to stop playing after severe coughing. Inspired by a quote from former football legend Johan Cruyff, the protagonist decides to throw away his cigarettes, symbolizing a transformative journey towards better lung health.

Crafted through a meticulous collaborative process, the comic underscores the importance of making scientific knowledge accessible to the public. It aims to shed light on respiratory diseases and the detrimental effects of tobacco consumption.

The comic’s creation was made possible through the invaluable contributions of various stakeholders, including patient associations and student groups.

To experience the visually engaging and impactful TOLIFE comic firsthand, download the files and delve into its powerful narrative.

Watch the interview with Raul Toran on the creation of the Comic!

Interview with Tognetti

Tognetti “TOLIFE final goal is to improve patient’s quality of life”

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21 February 2024

Alessandro Tognetti, professor of Bioengineering at the University of Pisa and Coordinator of the TOLIFE project, recently conducted an interview shedding light on the project’s progress.

Over the past 18 months, the TOLIFE project has achieved significant milestones. The team has focused on developing smart sensors and a data platform to monitor COPD patients’ daily activities. With pre-trials currently underway, the project stands on the cusp of transitioning from laboratory development to real-world application.

Looking ahead, the project aims to implement its developed technology in the field. By utilizing non-invasive sensors and advanced algorithms, the goal is to enhance the quality of care for COPD patients and improve their overall health outcomes.

For more insights into the TOLIFE project and its potential impact, watch the full interview with Professor Alessandro Tognetti.

Digital Health platform

TOLIFE Project Joins Digital Health Uptake Platform

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15 February 2024

The TOLIFE Projects experiences another important step toward success in its journey. Indeed, it has officially been registered in the Digital Health Uptake platform (DHU).

Understanding Digital Health Uptake (DHU)

DHU is a European initiative funded through the Digital Europe Programme, aimed at advancing the adoption and evolution of digital health solutions and services across Europe. It operates through three core pillars: RADAR, KNOWLEDGE COMMUNITY, and ACCELERATOR.

DHU RADAR

At the core of DHU lies RADAR, a platform mandated by the European Commission to serve as a central hub for digital health solutions in Europe and beyond. It offers a unique space for discovering, learning about, and publishing digital health innovations, as well as connecting with other stakeholders in the field. TOLIFE’s registration on the DHU RADAR presents a valuable opportunity to enhance the visibility of our AI solution within the European digital health landscape.

TOLIFE’s Registration on DHU

The decision to register TOLIFE on the DHU platform is rooted in the shared commitment to advancing digital health solutions. TOLIFE seeks to clinically validate an AI-driven solution capable of processing daily life patient data captured by unobtrusive sensors. By joining DHU, we gain access to a network of stakeholders, resources, and opportunities that will support our mission to optimize personalized treatment, predict exacerbations, assess health outcomes, and improve the quality of life for COPD patients.

In summary, the registration on the DHU platform signifies our dedication to leveraging digital health innovations and collaborations to address critical healthcare challenges, such as COPD management.

For more information about Digital Health Uptake, please visit digitalhealthuptake.eu.