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TOLIFE Project Kicks Off Clinical Study A for COPD

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9 July 2024

The TOLIFE project, aimed at revolutionizing the management of Chronic Obstructive Pulmonary Disease (COPD), has officially commenced its Clinical Study A. This milestone marks a significant step forward in the project’s mission to enhance the quality of life for COPD patients through personalized treatment and advanced technological solutions.

The Role of AI in COPD Management

TOLIFE leverages artificial intelligence (AI) to process daily life patient data captured by unobtrusive sensors. This AI-driven approach is designed to optimize personalized treatment, assess health outcomes, and ultimately improve the quality of life for COPD patients. By predicting and mitigating exacerbations, the TOLIFE platform aims to reduce mortality, enhance health-related quality of life, and lower healthcare costs.

Clinical Study A: A Key Component of TOLIFE

Clinical Study A is a crucial element of the TOLIFE project. The recruitment started in June 2024 and each participant will be monitored for 12 months. This study will focus on registering exacerbations and conducting periodic clinical examinations to provide essential clinical references for the AI tools being developed. The data collected from this study will be instrumental in:

  1. Developing a model to detect severe COPD exacerbations at an early stage.
  2. Creating a model to assess the impact of COPD and its comorbidities on patients’ health status and quality of life.

Progress and Next Steps

The Clinical Study A has successfully begun, with all necessary smart sensor kits delivered to Germany and Spain. Patients have started participating in the trial, and the platform is already collecting initial data for analysis. This early data collection is a promising start, indicating that the TOLIFE platform is on track to deliver valuable insights and improvements in COPD management.

By integrating advanced AI technologies with patient care, TOLIFE aspires to set a new standard in managing chronic diseases like COPD. The project’s commitment to enhancing patient outcomes through innovative solutions continues to drive its efforts forward.

Stay tuned for more updates on the progress and findings of Clinical Study A and other initiatives under the TOLIFE project.

Professor Tognetti presents TOLIFE Project at Robotics Festival in Pisa

TOLIFE Project presented at Robotics Festival in Pisa

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26 May 2024

Professor Tognetti, the coordinator of the TOLIFE Project, presented an engaging talk at the renowned Pisa Robotics Festival.

The presentation, titled “Intelligent Sensors and Artificial Intelligence for Managing Complex Chronic Diseases: The TOLIFE Project,” showcased the innovative work being done to transform healthcare management through advanced technology.

The TOLIFE Project aims to clinically validate an artificial intelligence (AI) solution to enable optimized and personalized treatment for patients with complex chronic diseases, with a particular focus on chronic obstructive pulmonary disease (COPD). By analyzing daily patient data captured from non-invasive smart devices (such as smartwatches, smartphones, smart mattress covers, smart shoes, and environmental units), TOLIFE predicts exacerbations, assesses patient health outcomes, and characterizes patient health status.

During the talk, Professor Tognetti provided an in-depth overview of the non-invasive smart devices selected for the TOLIFE clinical studies. The discussion emphasized the data collection framework, the rationale behind selecting each specific sensor, the raw data associated, and the health parameters detected.

The event garnered significant attention, drawing experts and enthusiasts from the fields of robotics and healthcare technology. Positive feedback highlighted the audience’s interest in the potential applications of TOLIFE’s cutting-edge solutions.

Stay updated with more news on the TOLIFE project as we continue to innovate in healthcare technology.

For more information about the festival and other talks, visit the Robotics Festival website here.

The first TOLIFE Comic is out now!

By Articles, Comic, News No Comments

3 April 2024

In a collaborative effort spearheaded by ISGlobal, a compelling comic has been developed as part of the TOLIFE project, aimed at advocating good lung health and raising awareness about the hazards of tobacco consumption. This initiative involved a diverse array of stakeholders including patients, caregivers, and student groups.

The comic, available in Spanish, Catalan, and English, portrays a man smoking on a park bench amidst lush greenery. As he reminisces about his youthful days playing football, he decides to join a group of kids on the field. Despite showcasing his football abilities, his smoking habit becomes a hindrance, forcing him to stop playing after severe coughing. Inspired by a quote from former football legend Johan Cruyff, the protagonist decides to throw away his cigarettes, symbolizing a transformative journey towards better lung health.

Crafted through a meticulous collaborative process, the comic underscores the importance of making scientific knowledge accessible to the public. It aims to shed light on respiratory diseases and the detrimental effects of tobacco consumption.

The comic’s creation was made possible through the invaluable contributions of various stakeholders, including patient associations and student groups.

To experience the visually engaging and impactful TOLIFE comic firsthand, download the files and delve into its powerful narrative.

Watch the interview with Raul Toran on the creation of the Comic!

Interview with Tognetti

Tognetti “TOLIFE final goal is to improve patient’s quality of life”

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21 February 2024

Alessandro Tognetti, professor of Bioengineering at the University of Pisa and Coordinator of the TOLIFE project, recently conducted an interview shedding light on the project’s progress.

Over the past 18 months, the TOLIFE project has achieved significant milestones. The team has focused on developing smart sensors and a data platform to monitor COPD patients’ daily activities. With pre-trials currently underway, the project stands on the cusp of transitioning from laboratory development to real-world application.

Looking ahead, the project aims to implement its developed technology in the field. By utilizing non-invasive sensors and advanced algorithms, the goal is to enhance the quality of care for COPD patients and improve their overall health outcomes.

For more insights into the TOLIFE project and its potential impact, watch the full interview with Professor Alessandro Tognetti.

Digital Health platform

TOLIFE Project Joins Digital Health Uptake Platform

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15 February 2024

The TOLIFE Projects experiences another important step toward success in its journey. Indeed, it has officially been registered in the Digital Health Uptake platform (DHU).

Understanding Digital Health Uptake (DHU)

DHU is a European initiative funded through the Digital Europe Programme, aimed at advancing the adoption and evolution of digital health solutions and services across Europe. It operates through three core pillars: RADAR, KNOWLEDGE COMMUNITY, and ACCELERATOR.

DHU RADAR

At the core of DHU lies RADAR, a platform mandated by the European Commission to serve as a central hub for digital health solutions in Europe and beyond. It offers a unique space for discovering, learning about, and publishing digital health innovations, as well as connecting with other stakeholders in the field. TOLIFE’s registration on the DHU RADAR presents a valuable opportunity to enhance the visibility of our AI solution within the European digital health landscape.

TOLIFE’s Registration on DHU

The decision to register TOLIFE on the DHU platform is rooted in the shared commitment to advancing digital health solutions. TOLIFE seeks to clinically validate an AI-driven solution capable of processing daily life patient data captured by unobtrusive sensors. By joining DHU, we gain access to a network of stakeholders, resources, and opportunities that will support our mission to optimize personalized treatment, predict exacerbations, assess health outcomes, and improve the quality of life for COPD patients.

In summary, the registration on the DHU platform signifies our dedication to leveraging digital health innovations and collaborations to address critical healthcare challenges, such as COPD management.

For more information about Digital Health Uptake, please visit digitalhealthuptake.eu.

Tech Tools for TOLIFE project

Insights from the TOLIFE Smart Sensors Workshop at CNR, Pisa

By Articles, News, Technical meeting No Comments

15 January 2024

In the heart of Pisa, at the esteemed CNR (Consiglio Nazionale delle Ricerche), the “TOLIFE Smart Sensors and Data Collection Platform” workshop unfolded over three enlightening days from January 10 to 12, 2024. This workshop offered a glimpse into the innovative strides being made within the TOLIFE project.

Day 1: Pioneering Protocols and Collaborative Endeavors 

Kicking off the workshop, CNR and the University of Pisa hosted an immersive exploration into crafting meticulous protocols for the “TOLIFE smart sensors and data collection platform” training. The collaborative effort aimed at standardizing procedures marks a significant stride in the journey towards testing innovative healthcare technologies on individuals dealing with chronic obstructive pulmonary disease (COPD).

In late February 2024, Clinical Study A will commence preliminary tests on healthy individuals, paving the way for subsequent testing on a selected group of 150 patients (Group A). This cohort will be monitored for 12 months, recording exacerbations and undergoing periodic clinical examinations, serving as vital references for the integrated Artificial Intelligence tools in the TOLIFE platform.

Day 2: Unveiling the TOLIFE Kit

The second day witnessed the unveiling of the comprehensive TOLIFE sensor kit, presented through the “TOLIFE Kit User Manual.” Professor Nicola Carbonaro took center stage, guiding dedicated volunteers through the installation, usage, and recharging processes of these groundbreaking devices. The TOLIFE kit includes a Wifi Router, Smart Mattress Cover with Bedroom Box, Smartwatch, Smartphone, Smart Shoes, and Spirometer.

Day 3: Revolutionizing Data Collection with the TOLIFE Platform

The third and final day delved into the design and technical functionalities of the TOLIFE platform, poised to revolutionize data collection with its smart sensors. The morning began with an in-depth presentation and discussion, setting the stage for a technical panel exploring the diverse functionalities of this innovative platform.

In summary, the TOLIFE Smart Sensors Workshop in Pisa marked a significant leap towards reshaping healthcare through groundbreaking technologies. The collaborative efforts of esteemed institutions, including the Barcelona Institute for Global Health (ISGlobal) and CNR, promise to usher in a new era of personalized and data-driven healthcare.

Stay tuned for more updates as TOLIFE continues its journey towards a healthier future!

TOLIFE, Pioneering Wearable Sensory Intelligence

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09 January 2024

Despite the ongoing global discourse on the ethical implications of artificial intelligence, a groundbreaking initiative, TOLIFE, is taking advantage of this cutting-edge technology to revolutionize healthcare.

In a recent feature in Exl, a magazine dedicated to showcasing excellence in technology, innovation, research, and enterprise, CNR engineer Marco Laurino provides deeper insights into the TOLIFE project.

Funded by the Horizon Europe framework of the European Union, TOLIFE aims to forge a platform that seamlessly integrates non-invasive artificial intelligence and sensor technology. The focus is on advancing the management and personalization of treatments for chronic obstructive pulmonary disease (COPD). Leveraging data from wearable sensors embedded in smartphones, smartwatches, and smart shoes, as well as strategically placed home devices, the project seeks to amass comprehensive Big Data reflecting patients’ daily activities.

This rich dataset, harmonized through a cloud-based platform, undergoes meticulous analysis by sophisticated algorithms. The objective is twofold:

  • to predict early onsets of disease exacerbations;
  • to provide continuous health monitoring for patients.

TOLIFE aspires to implement swift, tailored treatments that not only enhance the quality of life for patients but also contribute to significant reductions in healthcare costs. Spearheaded by the University of Pisa, the project brings together a dynamic, international consortium across multiple disciplines.

TOLIFE-Toolkit

New article of TOLIFE Project is out now!

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16 November 2023

We are pleased to inform you that a new article of TOLIFE Project is available online now on Repubblica Firenze – Italian Tech, an italian journal focused on innovative Italian technologies. The article entitled “Sensori nel materasso controllano i pazienti” talks about the sensor devices: the shoes, the smartwatch, the mattress, the spirometer+oximeter, all connected to the smartphone that gathers the data and sends them on the TOLIFE cloud platform.

New publication is out!

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01 June 2023

We are pleased to inform you that a Special Issue “Wearable Sensors and IoT Devices Applied in Daily Life” in available online now on MDPI journals! In this Special Issue, we invite original research papers aiming to promote novel and innovative applications and services that take advantage of IoT technologies to solve or improve activities of daily living in any domain. We are also interested in investigations of the impact of these IoT based services in different aspects of our daily life, such as wellbeing, social relationships, workability, leisure and sustainability.

More information available here >>